Risks & Symptoms

What are the symptoms of Ovarian Cancer?

Early diagnosis of ovarian cancers is significantly associated with better patient prognosis. Unfortunately, the majority of women diagnosed with ovarian cancer are already in advanced stages of the disease.

 

The symptoms of ovarian cancer are generally vague and may not be obvious, but the following may occur:


  • Vague abdominal pain or pressure
  • Feeling of abdominal fullness, gas, nausea, indigestion different to your normal sensations
  • Sudden abdominal swelling, weight gain or bloating
  • Persistent changes in bowel or bladder patterns
  • Low backache or cramps
  • Abnormal vaginal bleeding
  • Pain during intercourse
  • Unexplained weight loss

 

The majority of women who experience these early symptoms do not have cancer. However, it is important that you seek medical advice if the symptoms persist.



What are the risk factors?

The cause of most ovarian cancers is not known. However, certain risk factors increase the chance of developing the disease.

Age

  • Most women develop ovarian cancer after menopause and 50% are older than 65.

Lifestyle Factors

  • Caucasian women in industrialized countries with a higher standard of living have a higher risk
  • Dietary factors such as the consumption of meat, whole milk and animal fat have been associated with an increased risk in some studies; others have not found this connection.
  • The evidence suggests a small to moderate positive relation between an increased Body Mass Index (BMI) and occurrence of ovarian cancer

Ovulatory factors

Ovulation is the process by which an egg is released from the ovary for fertilization. Women who ovulate less frequently throughout their life appear to have a lower risk to develop ovarian cancer. Risk factors therefore include:

  • Having few or no children
  • Having started periods at an early age
  • Having the first child after the age of 30
  • Menopause occurring after the age of 50
  • The use of the combined oral contraceptive pill and breastfeeding lowers the risk slightly

Genetic factors

  • Between 5 and 10% of cases of ovarian cancer are believed to be attributable to hereditary factors. Most hereditary ovarian cancers are associated with mutations in the BRCA1 and BRCA 2 genes. Hereditary nonpolyposis colorectal cancer (HNPCC) syndrome is associated with ovarian cancer and other malignancies of the gastrointestinal and genitourinary system.
  • Women with one first degree relative (mother, aunt or sister) diagnosed with ovarian cancer and no confirmed family history have a lifetime risk of ovarian cancer which is at most moderately above the average for the general population; more than 97% of women in this group will not develop ovarian cancer.
  • Women with two or more first-degree relatives diagnosed with ovarian cancer or who have other risk factors like Ashkenazi Jewish ancestry have a potentially high risk of developing ovarian cancer and perhaps other cancers, such as breast cancer. But although the risk may be more than 3 times higher than the population average, the majority of women in this group will not develop ovarian cancer.

However, 95% of all ovarian cancer occurs in women without these risk factors and many women who have risk factors do not develop ovarian cancer.



What can you do?


There’s no screening test for ovarian cancer. A Pap test - used to detect cervical cancer - does not detect ovarian cancer.


If you’re still concerned about a persistent symptom, get a second opinion. No one knows your body like you do.



              

What are the statistics?

How is ovarian cancer diagnosed?

How is ovarian cancer treated?

How does one live with ovarian cancer?

                                                 

          



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© 2011 Ovarian Cancer Research Foundation   |   Level 1, TOK Corporate Centre, 459 Toorak Road, Toorak Victoria 3142   |   1300 682 742

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